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pentobarbital will lessen the extent or outcome of tamoxifen by influencing hepatic enzyme CYP2C9/ten metabolism. Use Caution/Observe.pentobarbital will lessen the level or impact of alosetron by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Significance Unknown.pentobarbital decreases amounts of toremifene by influencing hepatic/int